Eficácia do óleo essencial de Schinus terenbinthifolius (aroeira) no tratamento de DPOC

Abstract

Introduction: Chronic Obstructive Pulmonary Disease (COPD) is described as a clinical syndrome that involves pulmonar emphysema and chronic bronchitis and causes airway obstruction. It is the third leading cause of death in the world and is directly linked to exposure to toxic agentes such as cigarettes. When it does not lead to death, the diseare causes great function disability to the individual, with consequences such as early retirement and high rates of hospitalizations, representing na economic problem for the country. Aroeira is a plant widely used in folk medicine and is known for its anti-inflammatory, healing and analgesic properties. Objective: To analyze the effectiveness os essential oil os Schinus terenbinthifolius (aroeira) in the treatment of COPD. Methods: Experimental study. We used 25 rats that were induced to develop COPD by being exposed to cigarette smoke daily for 60 days in hermetically closed box for 30 uninterruped minutes and treated for 15 days divided into fivegroups, as follows: CTRL group exposed only to ambient air; CIGA group expoused to but untreated cigarette smoke; Group AO treated with aroeira essential oil 1 ml diluted in 10 ml of saline solution; group C treated with beclomethasone dipripionate (Clenil A) 1 ml diluted in 10 of saline solution; and OA+C group with the association of the two substances, 1 ml of oil + 1 ml of Clenil A+ 10 ml of saline solution. Result: The histological analysis demonstrated that the induction model was effective for the development of COPD in the animals and that the animals that were treated with mastic oil associated with beclomethasone dipropionate bad the worst performance of the treated groups. The aroeira group obtained the best result followed by the Clenil A group and both obtained results similar to the control group(CTLE) which was not smoke induced and can be considered a healthy group. Conclusion: Therefore, the ability of aroeira essential oil to stagnate the inflammatory processo of the lung parenchyma caused by toxic agentes such as cigarette smoke in rats is concluded.