Detecção eletroquímica de creatinina baseada em eletrodo de grafite de pilhas modificado com cobre

Abstract

The present work describes for the first time the manufacture of a creatinine electrochemical sensor based on copper modified graphite electrode from recyclable common batteries (GBE-Cu). GBE-Cu was prepared by electrodeposition of copper onto the graphite electrode and showed a high sensitivity toward creatinine oxidation, in addition to high stability, selectivity and repeatability. Copper was electrodeposited using chronoamperometric techniques at the potential of -0.7 V in a time of 100s. The graphite electrode modified with copper, was characterized by cyclic voltammetry and then used for electroanalytical detection of creatinine, observing a linear increase in oxidation currents as a function of the concentration of creatinine in the range of 26.5 mol L-1 to 150.3 mol L-1, with detection and quantification limits of 7.73 mol L -1 and 25.79 mol L-1, respectively. This work offers a promising strategy to manufacture a low-cost and reproducible sensor for the detection and quantification of creatinine.