Avaliação de membrana de Ximenia americana L., policaprolactona e osso bovino em pó como potencial andaime osteogênico

Abstract

Biomaterials, which can be synthesized from a variety of materials including metals, metal alloys, ceramics, polymers and materials of natural origin, are at the heart of significant innovations in the life sciences. This study focused on investigating the osteogenic capacity of membranes synthesized from Polycaprolactone (PCL), bovine bone powder and Ximenia americana L extract. The fibers were prepared from polymeric solutions and bovine bone matrix powder, subjected to magnetic stirring. , and later incorporated into Ximenia americana L. The resulting membranes were characterized using Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). In addition, swelling, bioactivity and cytotoxicity tests were carried out. The results indicated the presence of different functional groups in the samples, the formation of microfibers, osteogenic potential of the material and low cell viability, suggesting the need for further tests before clinical application.